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Ajit Verma

From Human Oncology

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Ajit Verma


Ajit Verma
Professor

600 Highland Avenue
K4/532
Madison, WI 53792

Telephone: 608-263-9136
Fax: N/A
E-mail:





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Administrative Support provided by Mary Marshall

Verma Lab

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  • DL Wheeler, KJ Ness, TD Oberly, and AK Verma, Protein Kinase C epsilon is linked to 12-O-tetradecanoylphorbol-13-acetate-induced Tumor Necrosis Factor alpha ectodomain shedding and to the development of metastatic squamous cell carcinoma in Protein Kinase C epsilon transgenic mice. (In press in Cancer Research).
  • DL Wheeler, KJ Ness, TD Oberley, and AK Verma, Inhibition of the development of metastatic squamous cell carcinoma in protein kinase C e transgenic mice by a-Difluoromethylornithine accompanied by marked hair follicle degeneration and hair loss. Cancer Research, 63:3037 (2003).
  • DL Wheeler, PJ Reddig, NE Dreckschmidt, and AK Verma, Protein Kinase C Delta-mediated signals to ornithine decarboxylase induction and to supression of skin tumor promotion are independent. Oncogene, 21:3620 (2002).
  • AP Jansen, NE Dreckschmidt, EG Verwiebe, DL Wheeler, TD Oberley, and AK Verma, Relation of teh induction of epidermal ornithine decarboxylase and hyperplasia to the different skin tumor-promotion susceptibilities of protein kinase C alpha, delta and epsilon transgenic mice. International Journal of Cancer: 93,635 (2001).
  • AP Jansen, EG Verwiebe, NE Dreckschmidt, DL Wheeler, TD Oberley, and AK Verma, Protein kinase C-epsilon transgenic mice: a unique model for metastatic squamous cell carcinoma. Cancer Research: 61, 808 (2001).
  • Reddig, P.J., Dreckschmidt, N.E., Zou, J., Bourguignon, S.E., Oberley, T.D., and Verma, A.K. Transgenic mice overexpressing protein kinase C epsilon in their epidermis exhibit reduced papilloma burden but enhanced carcinoma formation after tumor promotion. Cancer Research, 60: 595-602, 2000.
  • Redding, P.J., Dreckschmidt, N.E., Ahrens, H., Simsiman, R., Tseng, C.P., Zou, J., Oberly, T.., and Verma, A.K. Transgenic mice overexpressing protein kinase Cdelta in the epidermis are resistant to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Cancer Research, 59:5710-5718, 1999.

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