Harari Lab Recent Publications

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Search here for a complete listing of all annotated Harari publications (laboratory and clinical).

2007 Publications

• Allen GW, Saba C, Armstrong EA, Huang SM, Benavente S, Ludwig DL, Hicklin DJ, Harari PM. Insulin-like growth factor-I receptor signaling blockade combined with radiation. Cancer Res. 2007 Feb 1;67(3):1155-62 PMID: 17283150 article link

2006 publications

• Hoang T, Huang S, Armstrong E, Eickhoff JC, Harari PM. Augmentation of radiation response with the vascular targeting agent ZD6126. Int J Radiat Oncol Biol Phys. 2006 Apr 1;64(5):1458-65. PMID: 16488554 article link

• Chinnaiyan P, Allen GW, Harari PM. Radiation and new molecular agents, part II: targeting HDAC, HSP90, IGF-1R, PI3K, and Ras. Semin Radiat Oncol. 2006 Jan;16(1):59-64. Review. PMID: 16378908 article link

• Harari PM, Huang S. Radiation combined with EGFR signal inhibitors: head and neck cancer focus. Semin Radiat Oncol. 2006 Jan;16(1):38-44. Review. PMID: 16378905 article link

• Chinnaiyan P, Varambally S, Tomlins SA, Ray S, Huang S, Chinnaiyan AM, Harari PM.  Enhancing the antitumor activity of ErbB blockade with histone deacetylase (HDAC) inhibition. Int J Cancer. 2006 Feb 15;118(4):1041-50. PMID: 16152586 article link

2005 Publications

• Li J, Huang S, Armstrong EA, Fowler JF, Harari PM. Angiogenesis and radiation response modulation after vascular endothelial growth factor receptor-2 (VEGFR2) blockade. Int J Radiat Oncol Biol Phys. 2005 Aug 1;62(5):1477-85. PMID: 16029810 article link

• Chinnaiyan P, Vallabhaneni G, Armstrong E, Huang SM, Harari PM. Modulation of radiation response by histone deacetylase inhibition. Int J Radiat Oncol Biol Phys. 2005 May 1;62(1):223-9. PMID: 15850925 article link

• Chinnaiyan P, Huang S, Vallabhaneni G, Armstrong E, Varambally S, Tomlins SA, Chinnaiyan AM, Harari PM. Mechanisms of enhanced radiation response following epidermal growth factor receptor signaling inhibition by erlotinib (Tarceva). Cancer Res. 2005 Apr 15;65(8):3328-35. PMID: 15833866 article link
  

2004 Publications

• Huang S, Armstrong EA, Benavente S, Chinnaiyan P, Harari PM.  Dual-agent molecular targeting of the epidermal growth factor receptor (EGFR): combining anti-EGFR antibody with tyrosine kinase inhibitor. Cancer Res. 2004 Aug 1;64(15):5355-62.  PMID: 15289342 article link</td>

• Harari PM, Huang SM.  Combining EGFR inhibitors with radiation or chemotherapy: will preclinical studies predict clinical results? Int J Radiat Oncol Biol Phys. 2004 Mar 1;58(3):976-83. Review. PMID: 14967459 article link
  

• Harari PM, Huang SM. Searching for reliable epidermal growth factor receptor response predictors: commentary re M.K. Nyati et al., Radiosensitization by pan-ErbB inhibitor CI-1033 in vitro and in vivo. Clin. Cancer Res., 10: 691-700, 2004. Clin Cancer Res. 2004 Jan 15;10(2):428-32. Review. PMID: 14760061 article link
  

2002 Publications

• Huang SM, Li J, Harari PM. Molecular inhibition of angiogenesis and metastatic potential in human squamous cell carcinomas after epidermal growth factor receptor blockade. Mol Cancer Ther. 2002 May;1(7):507-14. PMID:12479268 article link

• Kies MS, Harari PM.; Cetuximab (Imclone/Merck/Bristol-Myers Squibb). Curr Opin Investig Drugs. 2002 Jul;3(7):1092-100. Review. PMID: 12186273

• Harari PM, Huang SM. Epidermal growth factor receptor modulation of radiation response: preclinical and clinical development. Semin Radiat Oncol. 2002 Jul;12(3 Suppl 2):21-6. Review. PMID: 12174341

• Huang SM, Li J, Armstrong EA, Harari PM. Modulation of radiation response and tumor-induced angiogenesis after epidermal growth factor receptor inhibition by ZD1839 (Iressa). Cancer Res. 2002 Aug 1;62(15):4300-6. PMID: 12154033 article link

2001 Publications

• Huang SM, Li J, Harari PM. Monoclonal antibody blockade of the epidermal growth factor receptor in cancer therapy. Cancer Chemother Biol Response Modif. 2001;19:339-52. Review. PMID: 11686022
  

• Harari PM, Huang SM.; Radiation response modification following molecular inhibition of epidermal growth factor receptor signaling. Semin Radiat Oncol. 2001 Oct;11(4):281-9. Review. PMID: 11677653
  

• Harari PM, Huang SM.; Head and neck cancer as a clinical model for molecular targeting of therapy: combining EGFR blockade with radiation. Int J Radiat Oncol Biol Phys.2001 Feb 1;49(2):427-33. PMID: 11173137 article link
  

2000 Publications

• Huang SM, Harari PM.  Modulation of radiation response after epidermal growth factor receptor blockade in squamous cell carcinomas: inhibition of damage repair, cell cycle kinetics, and tumor angiogenesis. Clin Cancer Res. 2000 Jun;6(6):2166-74. PMID: 10873065 article link

• Harari PM, Huang SM.; Modulation of molecular targets to enhance radiation. Clin Cancer Res. 2000 Feb;6(2):323-5. Review. PMID: 1069050 article link

1999 Publications

• Huang SM, Harari PM.; Epidermal growth factor receptor inhibition in cancer therapy: biology, rationale and preliminary clinical results. Invest New Drugs. 1999;17(3):259-69. Review. PMID: 10665478 article link

• Huang SM, Bock JM, Harari PM.; Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck. Cancer Res. 1999 Apr 15;59(8):1935-40. PMID: 10213503 article link