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Randal Tibbetts

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Randal Tibbetts



    Phone: (608) 262-0027

    Mailing Address:
    3059 Wi Institute Medical Research
    1111 Highland Ave
    Madison, WI 53705

Tibbetts Lab Page

Tibbetts Lab


  • BS, University of Minnesota (Chemistry; Biochemistry)
  • PhD, Northwestern University (Microbiology-Immunology)
  • Postdoctoral Fellow, Duke University (Cancer Biology)


  • DNA damage signaling and genome protection.
  • Functional characterization of ALS-associated genes

Recent Publications

Sang Hwa Kim, Anthony T Trinh, Michele Campaigne Larsen, Adam S Mastrocola, Colin R Jefcoate, Pierre R Bushel, Randal S Tibbetts
Tunable regulation of CREB DNA binding activity couples genotoxic stress response and metabolism.
Nucleic Acids Res.: 2016, 44(20);9667-9680

Bennett W Fox, Randal S Tibbetts
Neurodegeneration: Problems at the nuclear pore.
Nature: 2015, 525(7567);36-7

Lihong Zhan, Qijing Xie, Randal S Tibbetts
Opposing roles of p38 and JNK in a Drosophila model of TDP-43 proteinopathy reveal oxidative stress and innate immunity as pathogenic components of neurodegeneration.
Hum. Mol. Genet.: 2015, 24(3);757-72

Adam S Mastrocola, Sang Hwa Kim, Anthony T Trinh, Lance A Rodenkirch, Randal S Tibbetts
The RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damage.
J. Biol. Chem.: 2013, 288(34);24731-41

Anthony T Trinh, Sang Hwa Kim, Hae-yoon Chang, Adam S Mastrocola, Randal S Tibbetts
Cyclin-dependent kinase 1-dependent phosphorylation of cAMP response element-binding protein decreases chromatin occupancy.
J. Biol. Chem.: 2013, 288(33);23765-75