Kristin Bradley, MD headshot

Kristin Bradley, MD

Professor (CHS)

Department of Human Oncology

I am a professor in the Department of Human Oncology. In my clinical practice, I specialize in treating patients with gynecologic, hematologic and pediatric malignancies. I have a very busy brachytherapy practice. I work closely with gynecologic oncologists, hematologists, pediatric oncologists, radiologists and other specialists to best meet my individual patients’ needs.

In addition to my clinical practice, I am the Radiation Oncology Residency Program director. I also am involved with teaching medical students and undergraduates. Fellows from gynecologic oncology and pediatric oncology work with me on clinical rotations yearly.

I perform clinical research, primarily in the area of gynecologic radiation oncology, but I also have served as the principal investigator for a Children’s Oncology Group study on pediatric pontine gliomas.

Education

Residency, University of Wisconsin–Madison, Radiation Oncology (2004)

Transitional Year Intern, St. Luke’s Medical Center, Milwaukee, (2000)

MD, University of Wisconsin–Madison, Medicine (1999)

BS, University of Wisconsin–Madison, Molecular Biology (1994)

Academic Appointments

Associate Professor (CHS), Human Oncology (2010)

Assistant Professor (CHS), Human Oncology (2004)

Selected Honors and Awards

Madison Magazine Top Doctors (multiple years)

UW Health Patient Experience Physician Champion Award (2016)

UW Health Clinical Practice Excellence Award (2015)

Teacher of the Year Award, The Association of Residents in Radiation Oncology (2007)

Chief Resident, Radiation Oncology, University of Wisconsin (2004)

National Institutes of Health (NIH) Physician-Scientist Training Grant (2002–2003)

Medical School Class Co-President (1995–1996)

Medical Scholars Program, University of Wisconsin (1991–1994)

University of Wisconsin Full Academic Scholarship (1991–1994)

Boards, Advisory Committees and Professional Organizations

American Society for Therapeutic Radiology and Oncology (ASTRO) (2000–pres.)

American Society for Clinical Oncology (ASCO) (2000–pres.)

Children’s Oncology Group (2004–pres.)

American Brachytherapy Society (2006–pres.)

Central Nervous System Tumor Committee, Children’s Oncology Group (COG) (2006–pres.)

Radiation Oncology Committee, Children’s Oncology Group (COG) (2006–pres.)

Scientific Committee and Abstract Reviewer, Gynecologic Section, for Annual Meeting, American Society for Therapeutic Radiology and Oncology (ASTRO) (2008–pres.)

Radiological Society of North America (RSNA) (2007–pres.)

Member, National Comprehensive Cancer Network (NCCN) Cervical, Vulvar, and Uterine Cancers Panel (2016–pres.)

Scientific Program Committee, Annual Meeting of the American Brachytherapy Society (ABS) (2016–2017)

President, Wisconsin Society of Radiation Oncology (2010–2013)

Radiation Oncology Committee, Gynecologic Oncology Group (GOG) (2006–2012)

Item Writing Committee, Gynecologic Section, American Board of Radiology (ABR) – writing questions for use in future ABR Radiation Oncology board certification exams (2007–2012)

Scientific Committee and Abstract Reviewer, Radiation Oncology and Radiobiology Subcommittee, for Annual Meeting, Radiological Society of North America (RSNA) (2007–2012)

Vice President, Wisconsin Society of Radiation Oncology (2008–2010)

Secretary, Wisconsin Society of Radiation Oncology (2007–2008)

International Working Group for Image-Guided Gynecologic Brachytherapy (2006–2008)

Research Focus

Gynecologic Cancer, Hematologic Malignancies, Pediatric Malignancies


Dr. Kristin Bradley specializes in treating patients with gynecologic, hematologic and pediatric malignancies. She has a busy brachytherapy practice and works closely with gynecologic oncologists, hematologists, pediatric oncologists, radiologists and other specialists to best meet her patients’ needs. She also is the Radiation Oncology Residency Program director.

I participate in clinical research, evaluating ways to improve cancer care in patients with gynecologic, hematologic or pediatric cancers who are receiving radiation as a component of their treatment.

Novel Use of 0.35T ViewRay MRI-guidance for High Dose Rate Brachytherapy in the Treatment of Cervical Cancer

Image-guided adaptive brachytherapy for cervical cancer has resulted in improved outcomes and/or decreased toxicity rates for many cervical patients compared to prior 2D/fluoroscopic-based planning. We sought to evaluate the 0.35T MRI on our ViewRay system for brachytherapy and to compare dosimetry, time to treatment and image quality relative to diagnostic MRI and CT.

Two graphs comparing 0.35T MRI on ViewRay system for brachytherapy and to compare dosimetry, time to treatment and image quality relative to diagnostic MRI and CT.

We presented our findings in abstract form at ASTRO 2017 and manuscript has been submitted.

Severe Late Toxicities Following Concomitant Chemoradiotherapy Compared to Radiotherapy Alone in Cervical Cancer: An Inter-Era Analysis

We sought to compare rates of severe late toxicities following concomitant chemoradiotherapy and radiotherapy alone for cervical cancer. We found that compared to radiotherapy alone, concomitant chemoradiotherapy is associated with higher rates of severe vaginal and skeletal late toxicities.

 

Locations

University Hospitals and Clinics

I am the Radiation Oncology Residency Program director. I also am involved with teaching medical students and undergraduates. Fellows from gynecologic oncology and pediatric oncology work with me on clinical rotations yearly.

 

Radiation Oncology Residency Page
  • Radiation Therapy for Endometrial Cancer: An ASTRO Clinical Practice Guideline Practical radiation oncology
    Harkenrider MM, Abu-Rustum N, Albuquerque K, Bradfield L, Bradley K, Dolinar E, Doll CM, Elshaikh M, Frick MA, Gehrig PA, Han K, Hathout L, Jones E, Klopp A, Mourtada F, Suneja G, Wright AA, Yashar C, Erickson BA
    2022 Oct 21:S1879-8500(22)00273-9. doi: 10.1016/j.prro.2022.09.002. Online ahead of print.
  • Targeting the GTV in medically inoperable endometrial cancer using brachytherapy Brachytherapy
    Merfeld EC, Kuczmarska-Haas A, Burr AR, Witt JS, Francis DM, Ntambi J, Desai VK, Huang JY, Miller JR, Lawless MJ, Wallace CR, Anderson BM, Bradley KA
    2022 Aug 24:S1538-4721(22)00121-0. doi: 10.1016/j.brachy.2022.07.006. Online ahead of print.
  • NCCN Guidelines® Insights: Uterine Neoplasms, Version 3.2021 Journal of the National Comprehensive Cancer Network : JNCCN
    Abu-Rustum NR, Yashar CM, Bradley K, Campos SM, Chino J, Chon HS, Chu C, Cohn D, Crispens MA, Damast S, Diver E, Fisher CM, Frederick P, Gaffney DK, George S, Giuntoli R, Han E, Howitt B, Huh WK, Lea J, Mariani A, Mutch D, Nekhlyudov L, Podoll M, Remmenga SW, Reynolds RK, Salani R, Sisodia R, Soliman P, Tanner E, Ueda S, Urban R, Wethington SL, Wyse E, Zanotti K, McMillian NR, Motter AD
    2021 Aug 1;19(8):888-895. doi: 10.6004/jnccn.2021.0038.
  • Four Ways to Decrease Late Toxicity From Pelvic Radiation Therapy in Children and Young Adults Practical radiation oncology
    Blitzer GC, Bradley KA
    2021 Nov-Dec;11(6):434-440. doi: 10.1016/j.prro.2021.07.001. Epub 2021 Jul 16.
  • Rare tumors: Retinoblastoma, nasopharyngeal cancer, and adrenocorticoid tumors Pediatric blood & cancer
    Patel S, Vogel J, Bradley K, Chuba PJ, Buchsbaum J, Krasin MJ
    2021 May;68 Suppl 2:e28253. doi: 10.1002/pbc.28253.
  • Comparison of catheter reconstruction techniques for the lunar ovoid channels of the Venezia<sup>TM</sup> applicator Journal of contemporary brachytherapy
    Hansen J, Dunkerley D, Bradley K, Miller J, Huang J
    2020 Aug;12(4):383-392. doi: 10.5114/jcb.2020.98119. Epub 2020 Aug 21.
  • NCCN Guidelines Insights: Cervical Cancer, Version 1.2020 Journal of the National Comprehensive Cancer Network : JNCCN
    Abu-Rustum NR, Yashar CM, Bean S, Bradley K, Campos SM, Chon HS, Chu C, Cohn D, Crispens MA, Damast S, Fisher CM, Frederick P, Gaffney DK, Giuntoli R, Han E, Huh WK, Iii RL, Mariani A, Mutch D, Nagel C, Nekhlyudov L, Fader AN, Remmenga SW, Reynolds RK, Sisodia R, Tillmanns T, Ueda S, Urban R, Wyse E, McMillian NR, Motter AD
    2020 Jun;18(6):660-666. doi: 10.6004/jnccn.2020.0027.
  • Gestational Trophoblastic Neoplasia, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology Journal of the National Comprehensive Cancer Network : JNCCN
    Abu-Rustum NR, Yashar CM, Bean S, Bradley K, Campos SM, Chon HS, Chu C, Cohn D, Crispens MA, Damast S, Dorigo O, Eifel PJ, Fisher CM, Frederick P, Gaffney DK, Han E, Huh WK, Lurain JR, Mariani A, Mutch D, Nagel C, Nekhlyudov L, Fader AN, Remmenga SW, Reynolds RK, Sisodia R, Tillmanns T, Ueda S, Wyse E, McMillian NR, Scavone J
    2019 Nov 1;17(11):1374-1391. doi: 10.6004/jnccn.2019.0053.
  • Combining brachytherapy and immunotherapy to achieve in situ tumor vaccination: A review of cooperative mechanisms and clinical opportunities Brachytherapy
    Patel RB, Baniel CC, Sriramaneni RN, Bradley K, Markovina S, Morris ZS
    2019 Mar-Apr;18(2):240. doi: 10.1016/j.brachy.2019.01.004.
  • In Reply to Lin and Golden International journal of radiation oncology, biology, physics
    Jang S, Rosenberg SA, Bradley KA, Kimple RJ
    2018 Nov 1;102(3):672. doi: 10.1016/j.ijrobp.2018.06.043.
  • Combining brachytherapy and immunotherapy to achieve in situ tumor vaccination: A review of cooperative mechanisms and clinical opportunities Brachytherapy
    Patel RB, Baniel CC, Sriramaneni RN, Bradley K, Markovina S, Morris ZS
    2018 Nov-Dec;17(6):995-1003. doi: 10.1016/j.brachy.2018.07.004. Epub 2018 Aug 2.
    • More

      PMID:30078541 | PMC:PMC8292980 | DOI:10.1016/j.brachy.2018.07.004


      View details for PubMedID 30078541
  • Beyond 'charting outcomes' in the radiation oncology match: analysis of self-reported applicant data Medical education online
    Jang S, Rosenberg SA, Hullett C, Bradley KA, Kimple RJ
    2018 Dec;23(1):1489691. doi: 10.1080/10872981.2018.1489691.
    • More

      PMID:29943670 | PMC:PMC6022246 | DOI:10.1080/10872981.2018.1489691


      View details for PubMedID 29943670
  • A New Era of Image Guidance with Magnetic Resonance-guided Radiation Therapy for Abdominal and Thoracic Malignancies Cureus
    Mittauer K, Paliwal B, Hill P, Bayouth JE, Geurts MW, Baschnagel AM, Bradley KA, Harari PM, Rosenberg S, Brower JV, Wojcieszynski AP, Hullett C, Bayliss RA, Labby ZE, Bassetti MF
    2018 Apr 4;10(4):e2422. doi: 10.7759/cureus.2422.
  • Novel use of ViewRay MRI guidance for high-dose-rate brachytherapy in the treatment of cervical cancer Brachytherapy
    Ko HC, Huang JY, Miller JR, Das RK, Wallace CR, Costa AD, Francis DM, Straub MR, Anderson BM, Bradley KA
    2018 Jul-Aug;17(4):680-688. doi: 10.1016/j.brachy.2018.04.005. Epub 2018 Jun 7.
  • In Reply to Hamstra International journal of radiation oncology, biology, physics
    Rosenberg SA, Bradley KA, Kimple RJ
    2018 Apr 1;100(5):1293-1294. doi: 10.1016/j.ijrobp.2018.01.038.
  • The role of radiation therapy in the treatment of Stage II endometrial cancer: A large database study Brachytherapy
    Wojcieszynski AP, Hullett CR, Medlin EE, Taunk NK, Shabason JE, Brower JV, Chen S, Bekelman JE, Barroilhet LM, Bradley KA
    2018 Jul-Aug;17(4):645-652. doi: 10.1016/j.brachy.2018.02.001. Epub 2018 Apr 22.
  • Bone marrow suppression as a complication of total skin helical tomotherapy in the treatment of mycosis fungoides Radiation oncology (London, England)
    Schaff EM, Rosenberg SA, Olson SJ, Howard SP, Bradley KA
    2018 Apr 13;13(1):67. doi: 10.1186/s13014-018-1013-2.
  • Value of Elective Radiation Oncology Rotations: How Many Is Too Many? International journal of radiation oncology, biology, physics
    Jang S, Rosenberg SA, Hullet C, Bradley KA, Kimple RJ
    2018 Mar 1;100(3):558-559. doi: 10.1016/j.ijrobp.2017.10.052. Epub 2017 Nov 6.
    • More

      PMID:29413271 | PMC:PMC5806148 | DOI:10.1016/j.ijrobp.2017.10.052


      View details for PubMedID 29413271
  • Neck Rhabdoid Tumors: Clinical Features and Consideration of Autologous Stem Cell Transplant Journal of pediatric hematology/oncology
    Wolfe AD, Capitini CM, Salamat SM, DeSantes K, Bradley KA, Kennedy T, Dehner LP, Patel NJ
    2018 Jan;40(1):e50-e54. doi: 10.1097/MPH.0000000000000829.
    • More

      PMID:28375943 | PMC:PMC5624815 | DOI:10.1097/MPH.0000000000000829


      View details for PubMedID 28375943
  • Online patient information from radiation oncology departments is too complex for the general population Practical radiation oncology
    Rosenberg SA, Francis DM, Hullet CR, Morris ZS, Brower JV, Anderson BM, Bradley KA, Bassetti MF, Kimple RJ
    2017 Jan-Feb;7(1):57-62. doi: 10.1016/j.prro.2016.07.008. Epub 2016 Aug 1.
    • More

      PMID:27663932 | PMC:PMC5219938 | DOI:10.1016/j.prro.2016.07.008


      View details for PubMedID 27663932
  • Readability of Online Patient Educational Resources Found on NCI-Designated Cancer Center Web Sites Journal of the National Comprehensive Cancer Network : JNCCN
    Rosenberg SA, Francis D, Hullett CR, Morris ZS, Fisher MM, Brower JV, Bradley KA, Anderson BM, Bassetti MF, Kimple RJ
    2016 Jun;14(6):735-40. doi: 10.6004/jnccn.2016.0075.
  • Pitfalls in Imaging of Cervical Cancer Seminars in roentgenology
    Robbins J, Kusmirek J, Barroilhet L, Anderson B, Bradley K, Sadowski E
    2016 Jan;51(1):17-31. doi: 10.1053/j.ro.2015.11.001. Epub 2015 Nov 26.
  • In regard to Wu and Vapiwala et al International journal of radiation oncology, biology, physics
    Meyer JE, Dilling TJ, Amdur RJ, Strasser JF, Tendulkar R, Lee WR, Jani AB, Elshaikh M, Poppe MM, Takita C, Currey A, Cheng SK, Jagsi R, Kuo JV, Chen AM, Dragun AE, Bradley K, Beriwal S, Smith RP, Chen RC, Rosenzweig K, Kim S, Mehta K
    2016 Mar 15;94(4):858-9. doi: 10.1016/j.ijrobp.2015.12.001.
  • Multi-Institutional Implementation and Evaluation of a Curriculum for the Medical Student Clerkship in Radiation Oncology Journal of the American College of Radiology : JACR
    Committee GW, Golden DW, Braunstein S, Jimenez RB, Mohindra P, Spektor A, Ye JC, Members SG
    2016 Feb;13(2):203-9. doi: 10.1016/j.jacr.2015.06.036. Epub 2015 Sep 26.
    • More

      PMID:26410347 | PMC:PMC4744090 | DOI:10.1016/j.jacr.2015.06.036


      View details for PubMedID 26410347
  • Medical Student Perspectives on a Multi-institutional Clerkship Curriculum: A Report From the Radiation Oncology Education Collaborative Study Group International journal of radiation oncology, biology, physics
    Ye JC, Mohindra P, Spektor A, Krishnan MS, Chmura SJ, Howard AR, Viswanathan AN, MacDonald SM, Thaker NG, Das P, Mancini BR, Higgins SA, Braunstein S, Haas-Kogan D, Bradley KA, Hung AY, Thomas CR, Kharofa J, Wheatley M, Currey A, Parashar B, Du K, Jimenez RB, Golden DW
    2015 Jun 1;92(2):217-9. doi: 10.1016/j.ijrobp.2015.01.043.
    • More

      PMID:25968822 | PMC:PMC4768460 | DOI:10.1016/j.ijrobp.2015.01.043


      View details for PubMedID 25968822
  • Impact of adjuvant pelvic radiotherapy in stage I uterine sarcoma Anticancer research
    Magnuson WJ, Petereit DG, Anderson BM, Geye HM, Bradley KA
    2015 Jan;35(1):365-70.
  • Cervical brachytherapy technique for locally advanced carcinoma of the cervix in a patient with septate uterus Journal of contemporary brachytherapy
    Platta CS, Wallace C, Gondi V, Das R, Straub M, Al-Niaimi A, Applegate G, Bradley KA
    2014 Mar;6(1):76-81. doi: 10.5114/jcb.2014.40768. Epub 2014 Feb 19.
  • Predictive factors of recurrence following adjuvant vaginal cuff brachytherapy alone for stage I endometrial cancer Gynecologic oncology
    Dunn EF, Geye H, Platta CS, Gondi V, Rose S, Bradley KA, Anderson BM
    2014 Jun;133(3):494-8. doi: 10.1016/j.ygyno.2014.03.554. Epub 2014 Mar 20.
  • Radiation oncology residency selection: a targeted assessment of factor importance among fourth-year medical students International journal of radiation oncology, biology, physics
    Brower JV, Mohindra P, Bradley KA, Golden DW
    2014 Mar 15;88(4):967-8. doi: 10.1016/j.ijrobp.2013.12.020.
  • Successful management of female urethral carcinoma with radiation therapy and concurrent chemotherapy Gynecologic oncology case reports
    Magnuson WJ, Bradley K, Shaves M
    2011 Nov 4;2(1):1-3. doi: 10.1016/j.gynor.2011.10.006. eCollection 2011.
    • More

      PMID:24371597 | PMC:PMC3860990 | DOI:10.1016/j.gynor.2011.10.006


      View details for PubMedID 24371597
  • Adjuvant and definitive radiation therapy for primary carcinoma of the vagina using brachytherapy and external beam radiation therapy Journal of contemporary brachytherapy
    Platta CS, Anderson B, Geye H, Das R, Straub M, Bradley K
    2013 Jun;5(2):76-82. doi: 10.5114/jcb.2013.36177. Epub 2013 Jun 28.
  • Effects of treatment duration during concomitant chemoradiation therapy for cervical cancer International journal of radiation oncology, biology, physics
    Shaverdian N, Gondi V, Sklenar KL, Dunn EF, Petereit DG, Straub MR, Bradley KA
    2013 Jul 1;86(3):562-8. doi: 10.1016/j.ijrobp.2013.01.037. Epub 2013 Apr 2.
  • Motexafin-gadolinium and involved field radiation therapy for intrinsic pontine glioma of childhood: a children's oncology group phase 2 study International journal of radiation oncology, biology, physics
    Bradley KA, Zhou T, McNall-Knapp RY, Jakacki RI, Levy AS, Vezina G, Pollack IF
    2013 Jan 1;85(1):e55-60. doi: 10.1016/j.ijrobp.2012.09.004. Epub 2012 Oct 22.
    • More

      PMID:23092726 | PMC:PMC3529324 | DOI:10.1016/j.ijrobp.2012.09.004


      View details for PubMedID 23092726
  • Severe late toxicities following concomitant chemoradiotherapy compared to radiotherapy alone in cervical cancer: an inter-era analysis International journal of radiation oncology, biology, physics
    Gondi V, Bentzen SM, Sklenar KL, Dunn EF, Petereit DG, Tannehill SP, Straub M, Bradley KA
    2012 Nov 15;84(4):973-82. doi: 10.1016/j.ijrobp.2012.01.064. Epub 2012 Aug 14.
    • More

      PMID:22898381 | PMC:PMC3706199 | DOI:10.1016/j.ijrobp.2012.01.064


      View details for PubMedID 22898381
  • Patterns of pain and distress during high-dose-rate intracavity brachytherapy for cervical cancer The journal of supportive oncology
    Kwekkeboom KL, Dendaas NR, Straub M, Bradley KA
    2009 May-Jun;7(3):108-14.
  • The impact of hybrid PET-CT scan on overall oncologic management, with a focus on radiotherapy planning: a prospective, blinded study Technology in cancer research & treatment
    Kruser TJ, Bradley KA, Bentzen SM, Anderson BM, Gondi V, Khuntia D, Perlman SB, Tome WA, Chappell RJ, Walker WL, Mehta MP
    2009 Apr;8(2):149-58. doi: 10.1177/153303460900800208.
  • Motexafin gadolinium and involved field radiation therapy for intrinsic pontine glioma of childhood: a Children's Oncology Group phase I study Neuro-oncology
    Bradley KA, Pollack IF, Reid JM, Adamson PC, Ames MM, Vezina G, Blaney S, Ivy P, Zhou T, Krailo M, Reaman G, Mehta MP, Group CO
    2008 Oct;10(5):752-8. doi: 10.1215/15228517-2008-043. Epub 2008 Aug 20.
  • The effect of laparoscopic guidance on gynecologic interstitial brachytherapy Journal of minimally invasive gynecology
    Engle DB, Bradley KA, Chappell RJ, Conner JP, Hartenbach EM, Kushner DM
    2008 Sep-Oct;15(5):541-6. doi: 10.1016/j.jmig.2008.06.001. Epub 2008 Jul 26.
  • Impact of hybrid fluorodeoxyglucose positron-emission tomography/computed tomography on radiotherapy planning in esophageal and non-small-cell lung cancer International journal of radiation oncology, biology, physics
    Gondi V, Bradley K, Mehta M, Howard A, Khuntia D, Ritter M, Tomé W
    2007 Jan 1;67(1):187-95. doi: 10.1016/j.ijrobp.2006.09.033.
  • Radiation therapy for gynecologic malignancies Hematology/oncology clinics of North America
    Bradley KA, Petereit DG
    2006 Apr;20(2):347-61. doi: 10.1016/j.hoc.2006.01.019.
  • Quality assurance of treatment plans for interstitial and intracavitary high-dose-rate brachytherapy Brachytherapy
    Das RK, Bradley KA, Nelson IA, Patel R, Thomadsen BR
    2006 Jan-Mar;5(1):56-60. doi: 10.1016/j.brachy.2005.11.002.
  • Linear accelerator radiosurgery for trigeminal neuralgia Neurosurgery
    Richards GM, Bradley KA, Tomé WA, Bentzen SM, Resnick DK, Mehta MP
    2005 Dec;57(6):1193-200; discussion 1193-200. doi: 10.1227/01.neu.0000186015.01179.70.
  • Radiation therapy for leptomeningeal cancer Cancer treatment and research
    Mehta M, Bradley K
    2005;125:147-58. doi: 10.1007/0-387-24199-x_9.
  • Management of brain metastases Seminars in oncology
    Bradley KA, Mehta MP
    2004 Oct;31(5):693-701. doi: 10.1053/j.seminoncol.2004.07.012.
  • Megavoltage computed tomography imaging: a potential tool to guide and improve the delivery of thoracic radiation therapy Clinical lung cancer
    Welsh JS, Bradley K, Ruchala KJ, Mackie TR, Mañon R, Patel R, Wiederholt P, Lock M, Hui S, Mehta MP
    2004 Mar;5(5):303-6. doi: 10.3816/CLC.2004.n.010.

Contact Information

Kristin Bradley, MD

600 Highland Avenue,
Madison, WI 53792